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Microlenses as amplification for CCD-based detection devices for screening applications in biology, biochemistry, and chemistry

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Abstract

We describe the use of microlenses as amplification for CCD-based detection devices. The possible amplification of a signal in a reaction chamber of a nanoplate is estimated with a first-order approximation. This value was proved with a commercially available microlens and with a specially constructed microlens array made of glass hemispheres. Possible applications of this approach to amplification are given.

© 1998 Optical Society of America

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