Abstract

Changes in the response characteristics of the flash electroretinogram (ERG) of the human cone system were studied during the time course of adaptation to a cone-isolating ganzfeld background. During light adaptation, the amplitudes of the b- and i-waves increased, while the implicit time of the b-wave decreased. The amplitude of the a-wave and the implicit times of the a- and i -waves did not change systematically during light adaptation. Luminance-response functions for b-wave amplitude were obtained at discrete times following background onset and were analyzed using the hyperbolic equation R/R_max= Lⁿ/(Lⁿ+ Kⁿ). The increase in b-wave amplitude was characterized by increases in R_max, K, and n. The decrease in b-wave implicit time was of a similar magnitude at all flash luminances. The amplitude increase of the i-wave only occurred at moderate flash luminances. The results provide a basis for optimizing the clinical recording of cone-isolated single-flash ERGs.

© 1989 Optical Society of America

Level of Light Adaptation and the Human Electroretinogram

William R. Biersdorf and John C. Armington
J. Opt. Soc. Am. 50(1) 78-82 (1960)

Course of the Potential Change in the Human Electroretinogram during Light Adaptation

Heiichiro Kawabata
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Changes in the Human Electroretinogram during Early Dark Adaptation*

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Effects of background light on the human dark-adapted electroretinogram and psychophysical threshold

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Luminance-Duration Relationships in the Light-Adapted Electroretinogram

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J. Opt. Soc. Am. 48(6) 412-417 (1958)