Abstract

We have studied the influence of absorption, scattering, and refractive index of a phantom medium in conjunction with various beam diameters on the penetration depth of light at 633 nm. We used mixtures of Intralipid 10% (scattering medium) and Evans blue (absorbing medium). Measurements were performed in media with a scattering coefficient of 1 mm−1, an anisotropy factor of 0.71, absorption coefficients of 1.3 × 10−3, 0.01, and 0.05 mm−1, and a refractive index of 1.33. The experimental results were compared with an analytical solution of the fluence rate based on diffusion theory. We found good agreement (deviations of <10%) between theory and experiment for incident beam diameters between 10 and 60 mm.

© 1989 Optical Society of America

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References

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    [CrossRef] [PubMed]
  5. S. A. Prahl, “Light Transport in Tissue,” Ph.D. Dissertation, U. Texas at Austin (1988).
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    [CrossRef] [PubMed]
  7. S. L. Jacques, C. A. Alter, S. A. Prahl, “Angular Dependence of He-Ne Laser Light Scattering by Human Dermis,” Lasers Life Sci. 4, 309–333 (1987).
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    [CrossRef] [PubMed]

1988

W. M. Star, J. P. A. Marijnissen, M. J. C. Van Gemert, “Light Dosimetry in Optical Phantoms and in Tissues. 1: Multiple Flux and Transport Theory,” Phys. Med. Biol. 33, 437–454 (1988).
[CrossRef] [PubMed]

1987

W. M. Star, J. P. A. Marijnissen, H. Jansen, M. Keijzer, M. J. C. Van Gemert, “Light Dosimetry for Photodynamic Therapy by Whole Bladder Irradiation,” Photochem. Photobiol. 46, 619–624 (1987).
[CrossRef] [PubMed]

S. L. Jacques, C. A. Alter, S. A. Prahl, “Angular Dependence of He-Ne Laser Light Scattering by Human Dermis,” Lasers Life Sci. 4, 309–333 (1987).

1983

1976

Alter, C. A.

S. L. Jacques, C. A. Alter, S. A. Prahl, “Angular Dependence of He-Ne Laser Light Scattering by Human Dermis,” Lasers Life Sci. 4, 309–333 (1987).

Chandrasekhar, S.

S. Chandrasekhar, Radiative Transfer (Oxford U.P., London, 1960).

Ferwerda, H. A.

Groenhuis, R. A. J.

Ishimaru, A.

Jacques, S. L.

S. L. Jacques, C. A. Alter, S. A. Prahl, “Angular Dependence of He-Ne Laser Light Scattering by Human Dermis,” Lasers Life Sci. 4, 309–333 (1987).

Jansen, H.

W. M. Star, J. P. A. Marijnissen, H. Jansen, M. Keijzer, M. J. C. Van Gemert, “Light Dosimetry for Photodynamic Therapy by Whole Bladder Irradiation,” Photochem. Photobiol. 46, 619–624 (1987).
[CrossRef] [PubMed]

Johnson, C.

Keijzer, M.

W. M. Star, J. P. A. Marijnissen, H. Jansen, M. Keijzer, M. J. C. Van Gemert, “Light Dosimetry for Photodynamic Therapy by Whole Bladder Irradiation,” Photochem. Photobiol. 46, 619–624 (1987).
[CrossRef] [PubMed]

Marijnissen, J. P. A.

W. M. Star, J. P. A. Marijnissen, M. J. C. Van Gemert, “Light Dosimetry in Optical Phantoms and in Tissues. 1: Multiple Flux and Transport Theory,” Phys. Med. Biol. 33, 437–454 (1988).
[CrossRef] [PubMed]

W. M. Star, J. P. A. Marijnissen, H. Jansen, M. Keijzer, M. J. C. Van Gemert, “Light Dosimetry for Photodynamic Therapy by Whole Bladder Irradiation,” Photochem. Photobiol. 46, 619–624 (1987).
[CrossRef] [PubMed]

Prahl, S. A.

S. L. Jacques, C. A. Alter, S. A. Prahl, “Angular Dependence of He-Ne Laser Light Scattering by Human Dermis,” Lasers Life Sci. 4, 309–333 (1987).

S. A. Prahl, “Light Transport in Tissue,” Ph.D. Dissertation, U. Texas at Austin (1988).

Reynolds, L. O.

Star, W. M.

W. M. Star, J. P. A. Marijnissen, M. J. C. Van Gemert, “Light Dosimetry in Optical Phantoms and in Tissues. 1: Multiple Flux and Transport Theory,” Phys. Med. Biol. 33, 437–454 (1988).
[CrossRef] [PubMed]

W. M. Star, J. P. A. Marijnissen, H. Jansen, M. Keijzer, M. J. C. Van Gemert, “Light Dosimetry for Photodynamic Therapy by Whole Bladder Irradiation,” Photochem. Photobiol. 46, 619–624 (1987).
[CrossRef] [PubMed]

Ten Bosch, J. J.

Van Gemert, M. J. C.

W. M. Star, J. P. A. Marijnissen, M. J. C. Van Gemert, “Light Dosimetry in Optical Phantoms and in Tissues. 1: Multiple Flux and Transport Theory,” Phys. Med. Biol. 33, 437–454 (1988).
[CrossRef] [PubMed]

W. M. Star, J. P. A. Marijnissen, H. Jansen, M. Keijzer, M. J. C. Van Gemert, “Light Dosimetry for Photodynamic Therapy by Whole Bladder Irradiation,” Photochem. Photobiol. 46, 619–624 (1987).
[CrossRef] [PubMed]

Appl. Opt.

Lasers Life Sci.

S. L. Jacques, C. A. Alter, S. A. Prahl, “Angular Dependence of He-Ne Laser Light Scattering by Human Dermis,” Lasers Life Sci. 4, 309–333 (1987).

Photochem. Photobiol.

W. M. Star, J. P. A. Marijnissen, H. Jansen, M. Keijzer, M. J. C. Van Gemert, “Light Dosimetry for Photodynamic Therapy by Whole Bladder Irradiation,” Photochem. Photobiol. 46, 619–624 (1987).
[CrossRef] [PubMed]

Phys. Med. Biol.

W. M. Star, J. P. A. Marijnissen, M. J. C. Van Gemert, “Light Dosimetry in Optical Phantoms and in Tissues. 1: Multiple Flux and Transport Theory,” Phys. Med. Biol. 33, 437–454 (1988).
[CrossRef] [PubMed]

Other

S. Chandrasekhar, Radiative Transfer (Oxford U.P., London, 1960).

A. Ishimaru, Wave Propagation in Random Media, Vol. 1 (Academic, New York, 1978).

S. A. Prahl, “Light Transport in Tissue,” Ph.D. Dissertation, U. Texas at Austin (1988).

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