Abstract

The time resolved propagation of femtosecond and picosecond laser pulses within turbid tissues is simulated by a Monte Carlo model. The internal distribution of irradiance for an impulse vs a 4-ps pulse is specified at different times for various scattering coefficients and scattering phase functions. Such simulations provide time resolved dosimetry for predicting the distribution of single- and two-photon chemical reactions in turbid tissues. For femtosecond pulses in highly scattering tissues, two-photon reactions are dominated by the initial primary (unscattered, unabsorbed) pulse, and single-photon reactions are dominated by the scattered diffuse irradiance. For picosecond pulses in highly scattering tissues, both single- and two-photon reactions are dominated by the scattered irradiance.

© 1989 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Measurement of tissue optical properties by time-resolved detection of laser-induced transient stress

Alexander A. Oraevsky, Steven L. Jacques, and Frank K. Tittel
Appl. Opt. 36(1) 402-415 (1997)

Absorbed photodynamic dose from pulsed versus continuous wave light examined with tissue-simulating dosimeters

Brian W. Pogue, Lothar Lilge, Michael S. Patterson, Brian C. Wilson, and Tayyaba Hasan
Appl. Opt. 36(28) 7257-7269 (1997)

Experimental tests of a simple diffusion model for the estimation of scattering and absorption coefficients of turbid media from time-resolved diffuse reflectance measurements

Steen J. Madsen, Brian C. Wilson, Michael S. Patterson, Young D. Park, Steven L. Jacques, and Yaron Hefetz
Appl. Opt. 31(18) 3509-3517 (1992)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (9)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription