Abstract
Tomographic deconvolution phase microscopy (TDPM) is a promising
approach for 3D quantitative imaging of phase objects such as
biological cells and optical fibers. In the present work, the
alternating direction method of multipliers (ADMM) is applied to TDPM
to shorten its image acquisition and processing times while
simultaneously improving its accuracy. ADMM-TDPM is used to optimize
the image fidelity by minimizing Gaussian noise and by using total
variation regularization with the constraints of nonnegativity and
known zeros. ADMM-TDPM can reconstruct phase objects that are shift
variant in three spatial dimensions. ADMM-TDPM achieves speedups of 5x
in image acquisition time and greater than 10x in image processing
time with accompanying higher accuracy compared to TDPM.
© 2021 Optical Society of
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Data Availability
Data underlying the results presented in this paper are available in [47].
47. J. M. Long, J. Y. Chun, and T. K. Gaylord, “Image data for figures,” figshare (2021) [retrieved 12 September 2021] https://doi.org/10.6084/m9.figshare.c.5481870.
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