Abstract

We report the use of a common path phase sensitive spectral domain optical coherence tomography setup for the measurement of the refractive index (RI) of a biomimetic material (glucose solution in water having intralipid as the scattering medium) and a single biological cell (keratinocyte). The RI of glucose solutions could be measured with a precision of 0.00015, which corresponds to a precision of 2nm in the optical path length measurement in our setup. The precision obtained in the measurement of the RI of a single keratinocyte cell was 0.0004.

© 2011 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Swept source digital holographic phase microscopy

Shichao Chen, Junghyun Ryu, Kiho Lee, and Yizheng Zhu
Opt. Lett. 41(4) 665-668 (2016)

High-dynamic-range quantitative phase imaging with spectral domain phase microscopy

Jun Zhang, Bin Rao, Lingfeng Yu, and Zhongping Chen
Opt. Lett. 34(21) 3442-3444 (2009)

Application of maximum likelihood estimator in nano-scale optical path length measurement using spectral-domain optical coherence phase microscopy

S. M. R. Motaghian Nezam, C. Joo, G. J. Tearney, and J. F. de Boer
Opt. Express 16(22) 17186-17195 (2008)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (6)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Tables (1)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (2)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription