Abstract
We report on microscopic imaging of phospholipid membranes. To achieve nonlabel, noncontact, and high spatial resolution imaging of the membranes, we use optically excited localized surface plasmons as a virtual measurement probe to obtain the local refractive index. This enables significantly higher lateral resolution of . We reveal that the developed microscope has the capability of observing lipid bilayers with thickness of deposited into the gaps in a patterned lipid bilayer with thickness of . We find that the thickness resolution against the deposited lipid bilayer is .
© 2010 Optical Society of America
Full Article | PDF ArticleOSA Recommended Articles
Koyo Watanabe, Ryosuke Miyazaki, Goro Terakado, Takashi Okazaki, Kenichi Morigaki, and Hiroshi Kano
Biomed. Opt. Express 3(9) 2012-2020 (2012)
Goro Terakado, Jun Ning, Koyo Watanabe, and Hiroshi Kano
Appl. Opt. 52(14) 3324-3328 (2013)
Ruei-Yu He, Chun-Yu Lin, Yuan-Deng Su, Kuo-Chih Chiu, Nan-Shan Chang, Hua-Lin Wu, and Shean-Jen Chen
Opt. Express 18(4) 3649-3659 (2010)