Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Fourier analysis of light scattered by elongated scatterers

Not Accessible

Your library or personal account may give you access

Abstract

Biological stimulation of living cells is sometimes associated with morphological changes. A practical method is developed to monitor cell stimulation by means of their conformational changes through interpretation of the pattern of light scattered from a cell population. For this purpose a mathematical model is suggested that predicts the power spectrum from a population of elliptic objects with a given eccentricity. A computer simulation of that model is presented together with supporting experimental results of the simulation. The predicted and the measured spectra are in good agreement. This technique was applied to elongated cells that become circular on exposure to a human hormone, indicating the potential applicability of the method in biology and medicine. The method and the apparatus presented in this study could be applied to bioassays of cell systems that respond to a variety of stimulants and to trace quantitatively the structural changes that occur during biological processes.

© 1999 Optical Society of America

Full Article  |  PDF Article
More Like This
Paraxial analysis of light scattering by biological cells in a flow system

B. J. Pernick, M. R. Wohlers, and J. Mendelsohn
Appl. Opt. 17(20) 3205-3215 (1978)

Scattering of He–Ne laser light by an average-sized red blood cell

Stephanos V. Tsinopoulos and Demosthenes Polyzos
Appl. Opt. 38(25) 5499-5510 (1999)

Light scattering from cells: finite-difference time-domain simulations and goniometric measurements

Rebekah Drezek, Andrew Dunn, and Rebekah Richards-Kortum
Appl. Opt. 38(16) 3651-3661 (1999)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (7)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Tables (1)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (40)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved