Luminescent nanodiamond is attractive for targeted drug delivery and biolabelling due to its unique optical properties, low cytotoxicity, and biocompatible surface moieties. Advances in production of single-digit luminescent nanodiamonds will be reported. We will present a versatile bioconjugation protocol to dock biomolecules on the colloidal diamond, leading to demonstration of non-specific and specific internalisations in cells.

© 2011 Optical Society of America

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