Abstract

Standard lipoprotein measurements of triglycerides, total cholesterol, low-density lipoproteins (LDL), and high-density lipoproteins (HDL) fail to identify many lipoprotein abnormalities that contribute to cardiovascular heart diseases (CHD). Studies suggested that the presence of CHD is more strongly associated with the HDL subspecies than with total HDL cholesterol levels. The HDL particles can be collected in at least three subfractions, the HDL2b, HDL2a, and HDL3. More specifically, atherosclerosis is associated with low levels of HDL2. In this work, the optical spectroscopic properties of europium tetracycline (EuTc) complex in the presence of different HDL subspecies was studied. The results show that the europium spectroscopic properties in the EuTc complex are influenced by sizes and concentrations of subclasses. Eu³⁺ emission intensity and lifetime can discriminate the subfractions HDL3 and HDL2b.

© 2016 The Author(s)

Novel fluorescent probe for low density lipoprotein, based on the enhancement of Europium emission band

L. C. Courrol, A.M. Monteiro, F.R.O. Silva, L. Gomes, N.D. Vieira, M.A. Gidlund, and A.M. Figueiredo Neto
Opt. Express 15(11) 7066-7074 (2007)

Optical properties of silver nanoprisms and their influences on fluorescence of europium complex

Qingru Wang, Feng Song, Shangxin Lin, Jiadong Liu, Hongyan Zhao, Chao Zhang, Chengguo Ming, and Edwin Y. B. Pun
Opt. Express 19(8) 6999-7006 (2011)

Fraction estimation of small, dense LDL using autocorrelation function of dynamic light scattering

Suchin Trirongjitmoah, Toshihiro Sakurai, Kazuya Iinaga, Hitoshi Chiba, and Koichi Shimizu
Opt. Express 18(6) 6315-6326 (2010)

Enhancement of luminescent intensity of calixarene-oxetane polymer doped with europium complex

Bin Cai, Taeho Kim, Okihiro Sugihara, Kyoji Komatsu, and Toshikuni Kaino
Opt. Mater. Express 2(6) 717-722 (2012)

Measurements of optical properties of high-density media

Giovanni Zaccanti, Samuele Del Bianco, and Fabrizio Martelli
Appl. Opt. 42(19) 4023-4030 (2003)