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Optica Publishing Group
  • Applied Spectroscopy
  • Vol. 62,
  • Issue 3,
  • pp. 290-294
  • (2008)

Guest Aggregation Within Poly(L-lactic acid)/Pluronic P104 Thin Films

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Abstract

Rhodamine 6G (R6G) doped thin films composed of poly(L-lactic acid) (PLLA) and Pluronic P104 were spin cast onto glass microscope slides and characterized by ultraviolet–visible, steady-state, and time-resolved fluorescence spectroscopy. The results show that R6G aggregation within the film increases as the R6G concentration and P104 loading increases. These results suggest an approach for studying drug distributions (monomers, aggregates) within biodegradable polymer formulations.

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