Abstract

A method capable of measuring blood flow at precise depths within the skin is described. The method determines the static and the dynamic properties of light that is backscattered to small areas on the surface of the skin at several contiguous locations along the expected trajectory of laser-light propagation. From observations the method has been shown to be capable of determining physical characteristics that are unique to the different layers of the skin.

© 1999 Optical Society of America

Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography

Zhongping Chen, Thomas E. Milner, Shyam Srinivas, Xiaojun Wang, Arash Malekafzali, Martin J. C. van Gemert, and J. Stuart Nelson
Opt. Lett. 22(14) 1119-1121 (1997)

Experimental and theoretical laser-Doppler frequency spectra of a tissuelike model of a human head with capillaries

Robert Lohwasser and Gerald Soelkner
Appl. Opt. 38(10) 2128-2137 (1999)

Determination of optimal exposure time for imaging of blood flow changes with laser speckle contrast imaging

Shuai Yuan, Anna Devor, David A. Boas, and Andrew K. Dunn
Appl. Opt. 44(10) 1823-1830 (2005)

Doppler standard deviation imaging for clinical monitoring of in vivo human skin blood flow

Yonghua Zhao, Zhongping Chen, Christopher Saxer, Qimin Shen, Shaohua Xiang, Johannes F. de Boer, and J. Stuart Nelson
Opt. Lett. 25(18) 1358-1360 (2000)

Combined reflectance confocal microscopy/optical coherence tomography imaging for skin burn assessment

Nicusor Iftimia, R. Daniel Ferguson, Mircea Mujat, Ankit H. Patel, Ellen Ziyi Zhang, William Fox, and Milind Rajadhyaksha
Biomed. Opt. Express 4(5) 680-695 (2013)