Functionalization of silicon surfaces with small molecule bioreceptors to enable fieldable biosensing

Sanchao Liu; Xiaoming Ren; Matthew Coppock

doi:10.1364/SENSORS.2021.SW5H.3

OSA Optical Sensors and Sensing Congress 2021 (AIS, FTS, HISE, SENSORS, ES)
OSA Technical Digest (Optica Publishing Group, 2021),
paper SW5H.3
•https://doi.org/10.1364/SENSORS.2021.SW5H.3

Functionalization of silicon surfaces with small molecule bioreceptors to enable fieldable biosensing

Sanchao Liu, Xiaoming Ren, and Matthew Coppock

Optical Sensors 2021

Washington, DC United States
19–23 July 2021
ISBN: 978-1-943580-90-3

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Optical Sensors for Medical and Biological Applications (SW5H)

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S. Liu, X. Ren, and M. Coppock, "Functionalization of silicon surfaces with small molecule bioreceptors to enable fieldable biosensing," in OSA Optical Sensors and Sensing Congress 2021 (AIS, FTS, HISE, SENSORS, ES), S. Buckley, F. Vanier, S. Shi, K. Walker, I. Coddington, S. Paine, K. Lok Chan, W. Moses, S. Qian, P. Pellegrino, F. Vollmer, G. , J. Jágerská, R. Menzies, L. Emmenegger, and J. Westberg, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper SW5H.3.

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Abstract

We present our work of a surface modification method to universally incorporate molecular bioreceptors onto silicon surfaces through azidation and a Cu-free click reaction. The method is exemplified against streptavidin with biotin as the receptor.

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