We devised innovative, adaptable, bioplasmonic paper-based devices (BPDs) that diagnose Zika infection in patient serum via optical quantification of the localized surface plasmon resonance shift due to binding of patient’s anti-ZIKV-Nonstructural protein-1 IgG and IgM. By means of metal organic framework (MOF) technology, these BPDs do not require refrigeration and are stable at ambient temperature for extended time allowing use in resource-limited settings.

© 2017 Optical Society of America

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