Abstract

With development of biomedical nanotechnology, modification of traditional biomaterials with functional nanoparticles gets increasing interests. One promising aspect lies in the multi-functional scaffolds for tissue repair, which have been realized by integration of nanoparticles with the implantable materials so that the novel scaffold can play role of local stimulus, drug release and enhancing growth of cells. With the aggregation of nanoparticles scaling up, the interaction between individual units will play an increasingly important role in the collective property of nanoparticles as well as the influence upon the cells. Thus, the controlled assembly of nanoparticles in the macroscopic scale and the alteration of collective property after assembly have remained a critical issue.

© 2017 Optical Society of America