Abstract

The report focuses on the use of low coherence Michelson interferometer to obtain micro-vibration of the surface of the tissue surface for sensing the internal photoacoustic signal. Since the photoacoustic pressure is the first derivative of the change in tissue displacement caused by the photoacoustic pressure, the magnitude of the vibrational displacement of the surface of the biological tissue can be obtained to reflect the intensity of the photoacoustic signal. That is, the optical coherence intensity can be used to sense the micro-vibration of the tissue surface and which is proportional to the intensity of the photoacoustic wave inside the tissue, so that the intensity of the photoacoustic signal can be detected by the optical method. All-optical sensing detection can realize the multi-modal imaging system of photoacoustic imaging, optical coherence tomography and fluorescence imaging, which can obtain the absorption and scattering information of photons in biological tissues imultaneously.

© 2017 Optical Society of America