Abstract

A novel technique is presented for micro-endoscopy in which ultrasonic waves will alter the optical properties of tissue for sculpting virtual optical waveguides with graded refractive index profiles to guide and focus photons through the medium. Using this technique, images of target objects can be relayed through a turbid medium without implanting a physical endoscope. We demonstrate imaging of fluorescent objects with feature sizes as small as 22 µm through a scattering tissue phantom. The presented method can also enable in situ volumetric scanning of the medium by changing the pattern and intensity of ultrasonic waves. We demonstrate that arbitrary patterns of light can be sculpted in the target medium in the form of dipole, quadrupole and higher-order beam patterns using a multi-segment cylindrical ultrasonic array.

© 2020 The Author(s)

PDF Article  |   Presentation Video
More Like This
Ultrasonically-Assisted In Situ 3D Optical Imaging And Manipulation: Challenges And Opportunities To Access Deep Tissue

Matteo Giuseppe Scopelliti, Yasin Karimi, and Maysamreza Chamanzar
SM4H.5 CLEO: Science and Innovations (CLEO_SI) 2019

Ultrasonic Guiding and Steering of Light in Scattering Tissue

Matteo Giuseppe Scopelliti and Maysam Chamanzar
ATh1Q.2 CLEO: Applications and Technology (CLEO_AT) 2018

Micro-optical coherence tomography endoscopic imaging of rat colon ex vivo

Yuemei Luo, Nanshuo Wang, Dongyao Cui, Xiaojun Yu, En Bo, Xianghong Wang, Xinyu Liu, Jinhan Li, Shufen Chen, Si Chen, Shi Chen, and Linbo Liu
s1532 Conference on Lasers and Electro-Optics/Pacific Rim (CLEOPR) 2017

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Presentation Video

Presentation video access is available to:

  1. Optica Publishing Group subscribers
  2. Technical meeting attendees
  3. Optica members who wish to use one of their free downloads. Please download the article first. After downloading, please refresh this page.

Contact your librarian or system administrator
or
Log in to access Optica Member Subscription or free downloads


More Like This
Ultrasonically-Assisted In Situ 3D Optical Imaging And Manipulation: Challenges And Opportunities To Access Deep Tissue

Matteo Giuseppe Scopelliti, Yasin Karimi, and Maysamreza Chamanzar
SM4H.5 CLEO: Science and Innovations (CLEO_SI) 2019

Ultrasonic Guiding and Steering of Light in Scattering Tissue

Matteo Giuseppe Scopelliti and Maysam Chamanzar
ATh1Q.2 CLEO: Applications and Technology (CLEO_AT) 2018

Micro-optical coherence tomography endoscopic imaging of rat colon ex vivo

Yuemei Luo, Nanshuo Wang, Dongyao Cui, Xiaojun Yu, En Bo, Xianghong Wang, Xinyu Liu, Jinhan Li, Shufen Chen, Si Chen, Shi Chen, and Linbo Liu
s1532 Conference on Lasers and Electro-Optics/Pacific Rim (CLEOPR) 2017