Ratiometric Small Molecular Probes Based on Dual Emission for Intracellular Oxygen Sensing

Toshitada Yoshihara; Seiji Tobita

doi:10.1364/OMP.2017.OmTu3D.2

Optics in the Life Sciences Congress
OSA Technical Digest (online) (Optica Publishing Group, 2017),
paper OmTu3D.2
•https://doi.org/10.1364/OMP.2017.OmTu3D.2

Ratiometric Small Molecular Probes Based on Dual Emission for Intracellular Oxygen Sensing

Toshitada Yoshihara and Seiji Tobita

Optical Molecular Probes, Imaging and Drug Delivery 2017

San Diego, California United States
2–5 April 2017
ISBN: 978-1-943580-25-5

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Probes for Imaging and Sensing (OmTu3D)

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T. Yoshihara and S. Tobita, "Ratiometric Small Molecular Probes Based on Dual Emission for Intracellular Oxygen Sensing," in Optics in the Life Sciences Congress, OSA Technical Digest (online) (Optica Publishing Group, 2017), paper OmTu3D.2.

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Abstract

We developed ratiometic molecular oxygen probes based on fluorescent coumarin and phosphorescent iridium(III) complex. These probes were taken up into living cells and showed dual emission whose intensity ratio depends on the oxygen partial pressure.

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