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Conferences > OMP > 2013 > MT3C > MT3C.5

Autofluorescence Imaging Resolves Early Cancer Treatment Response In Vivo

Alex Walsh, Rebecca S. Cook, H. Charles Manning, Donna J. Hicks, Alec Lafontant, Carlos L. Arteaga, and Melissa C. Skala

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Abstract

NADH and FAD auto-fluorescence intensity and lifetime imaging are used to monitor breast cancer metabolism. In vivo imaging of xenograft tumors revealed metabolic differences in responsive but not resistant tumors treated with trastuzumab at earlier time points than FDG-PET.

© 2013 Optical Society of America

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