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A Novel Optical Metabolic Assay of Cancer Drug Efficacy in Primary 3D Tumor Cultures

Alex Walsh, Rebecca S. Cook, Carlos L. Arteaga, and Melissa C. Skala

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Abstract

Optical metabolic imaging of 3-dimensional cultures derived from primary human breast cancer tissue samples resolves cellular level response to cancer drugs and drug combinations. This approach could provide a powerful high-throughput drug screen for primary human tumors.

© 2013 Optical Society of America

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