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Optical redox imaging of endogenous contrast for tissue-engineered construct viability

Leng-Chun Chen, William R. Lloyd, Malavika Chandra, Kenji Izumi, Shiuhyang Kuo, Cynthia L. Marcelo, Stephen E. Feinberg, and Mary-Ann Mycek

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Abstract

Endogenous fluorescence redox imaging was developed to noninvasively assess cell viability in 3-dimensional tissue-engineered constructs prior to implantation. A lower redox ratio was observed from samples with higher proliferation.

© 2011 Optical Society of America

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