It is demonstrated that the etched core fiber Bragg grating sensor has sufficient sensitivity to detect the attachment of a monolayer of a low molecular weight molecule (APES) to the surface of the fiber and can differentiate this attachment from a polymeric attachment, as in the case for APTES. Hybridization and detection of DNA was successfully performed using the glutaraldehyde attachment chemistry. Also a new attachment chemistry based on glycobiology was demonstrated. Con A was successfully selectively attached to the fiber surface using glucose ligands and the attachment was detected by measuring a sizable change of the Bragg wavelength.

© 2006 IEICE

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