Combined Quantitative Phase Microscopy and Förster Resonance Energy Transfer for Analyzing Cell Ion Dynamics

Steven M. Parker; Hillel Price; Meghan Reynolds; Siyan He; Brenton D. Hoffman; Adam Wax

doi:10.1364/NTM.2021.NTh2C.1

Biophotonics Congress 2021
OSA Technical Digest (Optica Publishing Group, 2021),
paper NTh2C.1
•https://doi.org/10.1364/NTM.2021.NTh2C.1

Combined Quantitative Phase Microscopy and Förster Resonance Energy Transfer for Analyzing Cell Ion Dynamics

Steven M. Parker, Hillel Price, Meghan Reynolds, Siyan He, Brenton D. Hoffman, and Adam Wax

Novel Techniques in Microscopy 2021

Washington, DC United States
12–16 April 2021
ISBN: 978-1-943580-85-9

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Phase Microscopy II (NTh2C)

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S. M. Parker, H. Price, M. Reynolds, S. He, B. D. Hoffman, and A. Wax, "Combined Quantitative Phase Microscopy and Förster Resonance Energy Transfer for Analyzing Cell Ion Dynamics," in Biophotonics Congress 2021, C. Boudoux, K. Maitland, C. Hendon, M. Wojtkowski, K. Quinn, M. Schanne-Klein, N. Durr, D. Elson, F. Cichos, L. Oddershede, V. Emiliani, O. Maragò, S. Nic Chormaic, N. Pégard, S. Gibbs, S. Vinogradov, M. Niedre, K. Samkoe, A. Devor, D. Peterka, P. Blinder, and E. Buckley, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper NTh2C.1.

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Abstract

We demonstrate the use of quantitative phase microscopy and Förster resonance energy transfer for analyzing molecular and structural information simultaneously. Specifically, we focus on effects of ion channel modulation on signaling pathways and sub-cellular structure.

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