Collagen in Lentiginous Melanoma Characterized with Polarimetric Second-Harmonic Generation Microscopy

Martynas Riauka; Viktoras Mazeika; Mykolas Maciulis; Edvardas Zurauskas; Lukas Kontenis; Lukas Kontenis; Virginijus Barzda; Virginijus Barzda; Virginijus Barzda

doi:10.1364/NTM.2021.NTh1C.4

Biophotonics Congress 2021
OSA Technical Digest (Optica Publishing Group, 2021),
paper NTh1C.4
•https://doi.org/10.1364/NTM.2021.NTh1C.4

Collagen in Lentiginous Melanoma Characterized with Polarimetric Second-Harmonic Generation Microscopy

Martynas Riauka, Viktoras Mazeika, Mykolas Maciulis, Edvardas Zurauskas, Lukas Kontenis, and Virginijus Barzda

Novel Techniques in Microscopy 2021

Washington, DC United States
12–16 April 2021
ISBN: 978-1-943580-85-9

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Polarization and Collagen (NTh1C)

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M. Riauka, V. Mazeika, M. Maciulis, E. Zurauskas, L. Kontenis, and V. Barzda, "Collagen in Lentiginous Melanoma Characterized with Polarimetric Second-Harmonic Generation Microscopy," in Biophotonics Congress 2021, C. Boudoux, K. Maitland, C. Hendon, M. Wojtkowski, K. Quinn, M. Schanne-Klein, N. Durr, D. Elson, F. Cichos, L. Oddershede, V. Emiliani, O. Maragò, S. Nic Chormaic, N. Pégard, S. Gibbs, S. Vinogradov, M. Niedre, K. Samkoe, A. Devor, D. Peterka, P. Blinder, and E. Buckley, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper NTh1C.4.

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Abstract

Polarimetric second-harmonic generation (SHG) microscopy analysis of cancerous and normal tissues revealed the differences in SHG intensity, achiral susceptibility ratio and fiber orientation distribution suggesting an altered collagen structure.

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