Nonlinear microscopy and population density modeling of tumor cell metabolism

Melissa C. Skala

doi:10.1364/NTM.2015.NT4C.2

Optics in the Life Sciences
OSA Technical Digest (online) (Optica Publishing Group, 2015),
paper NT4C.2
•https://doi.org/10.1364/NTM.2015.NT4C.2

Nonlinear microscopy and population density modeling of tumor cell metabolism

Melissa C. Skala

Novel Techniques in Microscopy 2015

Vancouver Canada
12–15 April 2015
ISBN: 978-1-55752-954-1

From the session
Nonlinear Optical Microscopy II (NT4C)

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M. C. Skala, "Nonlinear microscopy and population density modeling of tumor cell metabolism," in Optics in the Life Sciences, OSA Technical Digest (online) (Optica Publishing Group, 2015), paper NT4C.2.

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Abstract

Multiphoton fluorescence lifetime microscopy provides unique insights into cellular-level metabolic heterogeneities. We exploit these techniques along with population density modeling to monitor heterogeneities in tumor response to anti-cancer drug treatments in vivo and in vitro.

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