Abstract

Super-resolution optical microscopy has some incomparable comprehensive advantages over various other microscopic technologies such as electron microscopy, atomic force microscopy and so on, especially in the study of biological molecules, pathways and events in live cells and tissues. In this report, we present a novel structured illumination microscopy (SIM) based on digital micromirror device (DMD) fringe projection with the low-coherence LED light as illumination source. A 90nm in-plane resolution was achieved with gold nano-particles and BPAE cells.

© 2013 Optical Society of America