We present a Digital Holographic Interferometry (DHI) system to measure low variations of concentrations from solutions of Plasmid and RNAs. A first hologram records a wave front coming from light crossing a cylindrical glass container filled with a certain concentration solution of Plasmid and RNAs, a second hologram is recorded corresponding to a concentration of the solution slightly changed. The difference phase maps is obtained by correlate the holograms, this provides information about of variations of concentration in the liquids. The system is simple, robust and provides good accurate measurements.

© 2014 Optical Society of America

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