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Optica Publishing Group
  • Laser Applications to Chemical and Environmental Analysis
  • Technical Digest (Optica Publishing Group, 2004),
  • paper TuC4

Multidimensional tissue imaging by matrix assisted laser desorption/ionization-ion mobility-mass spectrometry: advantages, challenges, and prospects for proteomics

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Abstract

MALDI-imaging mass spectrometry correlates detailed analyte information with spatial distribution in biological tissue sections. By combining post-ionization ion mobility separation with mass analysis, difficult peak assignments arising from spectrum congestion are alleviated.

© 2004 Optical Society of America

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