Abstract
Label-free measurements enable the observation of live samples such as cell cultures without requiring additional processing steps as for example loading contrast agents, or cell fixation. This makes it possible to assess the sample state in different conditions, such as during drug stimulation, without influence of external protocols on cell health. However, the absence of contrast agent usually makes label-free systems less specific than measurements which can have chemical-specificity by the inserted dyes.
© 2015 Japan Society of Applied Physics, Optical Society of America
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