Abstract
Titanium (Ti) is an attractive biomaterial because of its high strength. However, Ti has problems for long term applications and biofunction; therefore, its biocompatibility must be improved. Controlling the cell spreading on biomaterials is one of the useful methods to improve the biocompatibility of Ti plates. Increasing endothelial cell functions, anisotropic morphogenesis of bone tissue and control of differentiation have been achieved for biomaterials by the control of cell spreading. Thus, the control of cell spreading on biomaterials is important for the development of new functional biomaterials. The formation of periodic nanostructures on biomaterials is a useful method for the control of cell spreading.
© 2014 Japan Society of Applied Physics, Optical Society of America
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