Abstract

Injection of foreign materials, e.g., genes, enzymes, antibodies, and drugs, into individual cells has found significant applications as an important embodiment of bio-manipulation. Matsuoka et al. developed a robot and relevant devices that enabled efficient injection even into individual cells and the quantity of injected material can be controlled at femto gram level [1]. They have succeeded in evaluating the utility of decoy oligodeoxynucleotide delivery via femtoinjection in an embryonic stem cell in which Venus fluorescent protein was expressed under the control of the tet-off system [2].

© 2014 Japan Society of Applied Physics, Optical Society of America