Waveguide-based Detection of Protease Activity using Surface-Enhanced Raman Spectroscopy

Nina Turk; Nina Turk; Ali Raza; Ali Raza; Ali Raza; Pieter Wuytens; Pieter Wuytens; Pieter Wuytens; Hans Demol; Hans Demol; Michiel Van Daele; Christophe Detavernier; Andre Skirtach; Andre Skirtach; Kris Gevaert; Kris Gevaert; Roel Baets; Roel Baets

doi:10.1364/FIO.2020.FM7B.6

Frontiers in Optics / Laser Science
OSA Technical Digest (Optica Publishing Group, 2020),
paper FM7B.6
•https://doi.org/10.1364/FIO.2020.FM7B.6

Waveguide-based Detection of Protease Activity using Surface-Enhanced Raman Spectroscopy

Nina Turk, Ali Raza, Pieter Wuytens, Hans Demol, Michiel Van Daele, Christophe Detavernier, Andre Skirtach, Kris Gevaert, and Roel Baets

Frontiers in Optics 2020

Washington, DC United States
14–17 September 2020
ISBN: 978-1-943580-80-4

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Optical Waveguides and Endoscopy (FM7B)

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N. Turk, A. Raza, P. Wuytens, H. Demol, M. Van Daele, C. Detavernier, A. Skirtach, K. Gevaert, and R. Baets, "Waveguide-based Detection of Protease Activity using Surface-Enhanced Raman Spectroscopy," in Frontiers in Optics / Laser Science, B. Lee, C. Mazzali, K. Corwin, and R. Jason Jones, eds., OSA Technical Digest (Optica Publishing Group, 2020), paper FM7B.6.

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Abstract

We used a nanoplasmonic slot waveguide for the first time demonstration of waveguide-based detection of protease activity using Surface-Enhanced Raman Spectroscopy (SERS), paving the way for an integrated lab-on-a-chip protease activity monitoring.

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