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Conferences > FiO > 2016 > FF3A > FF3A.3

Disease Modeling in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes Using High-Throughput All-Optical Dynamic Cardiac Electrophysiology

Aleksandra Klimas, Yiyang Wu, Christina M. Ambrosi, Jinzhu Yu, John C. Williams, Harold Bien, Gholson J. Lyon, and Emilia Entcheva

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Abstract

We present an all-optical high-throughput system for phenotyping and monitoring iPSC-CMs, with capabilities for performing personalized cardiotoxicity screening. We demonstrate the system’s utility for characterizing a new disease model in iPSC-CMs.

© 2016 Optical Society of America

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