Teflon AF® tubing has been used as a liquid-core-optical-fiber(LCOF) to enhance the strength of Raman signals collected from urine samples. Data were collected from LCOF and traditional cuvette geometries. Creatinine and ethanol predictions in urine samples have been made using chemometric analysis. The improve in signal-to-noise-ratio(S/N) leads to better root-mean-square-error-prediction(RMSEP).

© 2004 Optical Society of America

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