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GRIN lenses for deep in vivo multiphoton imaging

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Abstract

Needle-like gradient index lenses are shown to be effective for acquiring multiphoton images from millimeters to centimeters deep in anesthetized animals. We present in vivo two-photon images in mouse of ovaries, of neurons from cortical layer V and hippocampus, and of capillaries several millimeters deep in the brain.

© 2003 Optical Society of America

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