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In recent years, DNA nanotechnology has matured to enable robust production of complex nanostructures and hybrid materials. Especially, the DNA origami technique yields robust and reproducible nanostructures that are easily produced by self-assembly in aqueous buffers. We have combined DNA nanotechnology with sensitive optical detection to create functional nano-devices such as nanoscopic rulers for superresolution microscopy and energy transfer switches [1-3]. DNA origamis are also used to construct nanoscale force balances with FRET readout or for single-molecule placement in zeromode waveguides using nanoadapters [4].
© 2015 IEEE
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