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Conferences > ECBO > 2021 > EW3A > EW3A.2
  • European Conferences on Biomedical Optics 2021 (ECBO)
  • OSA Technical Digest (Optica Publishing Group, 2021),
  • paper EW3A.2

Quantitative Measurement of Low-Concentration Analytes Using Raman Spectroscopy During Droplet Evaporation for Therapeutic Drug Monitoring

Sora Tomita, Terumasa Ito, Kazuyuki Iwaikawa, Gen Hayase, Daisuke Yoshino, and Kazuhiko Misawa

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Abstract

We propose a new method for therapeutic drug monitoring using Raman spectroscopy to quantify the concentration of analytes during droplet evaporation. The proposed method is demonstrated for quantitative measurement of methotrexate down to 0.5 mM.

© 2021 The Author(s)

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