Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

High accuracy platelet counting using lensfree imaging

Not Accessible

Your library or personal account may give you access

Abstract

Flow cytometry is the main technology used in hematology analyzers. However, this technology requires bulky and complex hardware systems. Lens-free imaging is an emerging microscopy technique based on a simple and compact in-line holography setup. This technique enables to image a large field-of-view (≈30mm2) leading to statistical counting (>10 000 cells) in a single-shot acquisition consistent with performances required in hematology. We report high accuracy platelet count in 54 platelet-rich plasma samples. This accuracy can be achieved through a wise choice of the illumination spectral properties and an optimized algorithmic chain dedicated to small pure phase objects.

© 2019 SPIE/OSA

PDF Article
More Like This
Simultaneous multiscale and bimodal imaging using lensfree microscopy

Matthieu Leroy, Isaure de Kernier, Thomas Bordy, Ondrej Mandula, Cedric Allier, Jean-Marc Dinten, Serge Monneret, and Pierre Blandin
104130C European Conference on Biomedical Optics (ECBO) 2017

Design and evaluation of two imaging systems for very wide field fluorescence microscopy

Isaure de Kernier, Nelly Rongeat, Sophie Morales, Serge Monneret, and Pierre Blandin
11075_9 European Conference on Biomedical Optics (ECBO) 2019

Quantitative Imaging of Platelet Aggregation in a Microchannel Using an Interfacial Collision Reactor

Taisuke Hirono, Shinpei Okawa, and Yukio Yamada
BTuF31 Biomedical Optics (BIOMED) 2008

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved