Mechanical property of a cell is investigated from reaction force generated on a particle fixed on a cell by moving with optical tweezers. This system is called as cell palpation system. By using of this system we can measure mechanical property at a desired location on a cell surface just by locating the probe particle with optical tweezers. We have investigated focal adhesion formation through mechanical property measurement after initiation of touching by the probe particle.

© 2013 SPIE

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