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Optica Publishing Group
  • Diffuse Optical Imaging IV
  • SPIE Proceedings (Optica Publishing Group, 2013),
  • paper 87990R

Development and evaluation of a multislice fluorescence molecular tomography using finite element method

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Abstract

Fluorescence molecular tomography is a novel approach that allows small animal imaging for early detection of cancer. However, challenges still remain in the improvement of the FMT software and hardware. In this work, a multislice FMT imaging system was developed and a finite element software with the modified calibration method was adapted to the geometry system. Phantom experiments are performed to verify the feasibility of the proposed method. The results demonstrate that the spatial resolution of the imaging system is less than 0.5mm and acquisition data time 30 minutes. In conclusion, The FMT system is capable to quantify 3D dye distribution using the well documented finite element software.

© 2013 SPIE

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