Using 2D correlation and multivariate analysis combined with plasmonic effects to expand the use of Raman microspectroscopy in biomedical applications

Monica Marro; Saurabh Raj; Satish Rao; Alice Taubes; Pablo Villoslada; Dmitri Petrov; Dmitri Petrov

doi:10.1364/ECBO.2011.80871H

Clinical and Biomedical Spectroscopy and Imaging II
Proceedings of SPIE-OSA Biomedical Optics (Optica Publishing Group, 2011),
paper 80871H
•https://doi.org/10.1364/ECBO.2011.80871H

Using 2D correlation and multivariate analysis combined with plasmonic effects to expand the use of Raman microspectroscopy in biomedical applications

Monica Marro, Saurabh Raj, Satish Rao, Alice Taubes, Pablo Villoslada, and Dmitri Petrov

European Conference on Biomedical Optics 2011

Munich Germany
22–26 May 2011
ISBN: 9780819486844

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CLINICAL AND PRECLINICAL DIAGNOSTICS II (CPDII)

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M. Marro, S. Raj, S. Rao, A. Taubes, P. Villoslada, and D. Petrov, "Using 2D correlation and multivariate analysis combined with plasmonic effects to expand the use of Raman microspectroscopy in biomedical applications," in Clinical and Biomedical Spectroscopy and Imaging II, N. Ramanujam and J. Popp, eds., Vol. 8087 of Proceedings of SPIE-OSA Biomedical Optics (Optica Publishing Group, 2011), paper 80871H.

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Abstract

We show that Surface Enhanced Raman spectroscopy (SERS) combined with 2D correlation and multivariate analysis provides considerable progress in using Raman microspectroscopy for cutting edge biomedical research applications such as treatment delivering in cancer living cells, the diagnosis of retina neuroinflamed tissue and the study of elastic properties of single DNA molecules.

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