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Conferences > ECBO > 2003 > CAI > 5140_152

Imaging of cartilage degeneration in vivo using ultrahigh resolution OCT

Paul Herz, Stephane Bourquin, Pei-lin Hsiung, Tony Ko, Karl Schneider, James Fujimoto, Samuel Adams, Mark Roberts, Nirlep Patel, and Mark Brezinski

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Abstract

Ultrahigh resolution OCT is used to visualize experimentally induced osteoarthritis in a rat knee model. Using a Cr4+:Forsterite laser, ultrahigh image resolutions of 5um are achieved in vivo. Progression of osteoarthritic remodeling and cartilage degeneration are quantified. The utility of OCT for the assessment of cartilage integrity is demonstrated.

© 2003 SPIE

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