Multimodal multiphoton microscopy for protein crystal detection based on two-color ultrafast fiber laser source

Hsiang-Yu Chung; Hsiang-Yu Chung; Hsiang-Yu Chung; Qing-di Cheng; Robin Schubert; Robin Schubert; Robin Schubert; Shih-Hsuan Chia; Shih-Hsuan Chia; Franz X. Kärtner; Franz X. Kärtner; Franz X. Kärtner; Franz X. Kärtner; Guoqing Chang; Christian Betzel; Christian Betzel

doi:10.1364/CLEO_AT.2021.AF2Q.1

Conference on Lasers and Electro-Optics
OSA Technical Digest (Optica Publishing Group, 2021),
paper AF2Q.1
•https://doi.org/10.1364/CLEO_AT.2021.AF2Q.1

Multimodal multiphoton microscopy for protein crystal detection based on two-color ultrafast fiber laser source

Hsiang-Yu Chung, Qing-di Cheng, Robin Schubert, Shih-Hsuan Chia, Franz X. Kärtner, Guoqing Chang, and Christian Betzel

CLEO: Applications and Technology 2021

San Jose, California United States
9–14 May 2021
ISBN: 978-1-943580-91-0

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New Technologies for Optical Imaging and Sensing (AF2Q)

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H. Chung, Q. Cheng, R. Schubert, S. Chia, F. X. Kärtner, G. Chang, and C. Betzel, "Multimodal multiphoton microscopy for protein crystal detection based on two-color ultrafast fiber laser source," in Conference on Lasers and Electro-Optics, J. Kang, S. Tomasulo, I. Ilev, D. Müller, N. Litchinitser, S. Polyakov, V. Podolskiy, J. Nunn, C. Dorrer, T. Fortier, Q. Gan, and C. Saraceno, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper AF2Q.1.

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Abstract

We demonstrate label-free multiphoton microscopy including harmonic generation and three-photon excitation fluorescence to score protein crystals based on a novel fiber laser source that emits femtosecond pulses at 775 nm and 1300 nm.

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