Elemental Mapping of Paraffin-Embedded Ductal Carcinoma Using Laser-Induced Breakdown Spectroscopy

Xiaohui Li; Xiaohui Li; Xue Chen; Yao Zhang; Yao Zhang; Sibo Yang; Sibo Yang; Guodong Yao; Aichun Liu; Xin Yu; Xin Yu

doi:10.1364/CLEO_AT.2020.AM4I.2

Conference on Lasers and Electro-Optics
OSA Technical Digest (Optica Publishing Group, 2020),
paper AM4I.2
•https://doi.org/10.1364/CLEO_AT.2020.AM4I.2

Elemental Mapping of Paraffin-Embedded Ductal Carcinoma Using Laser-Induced Breakdown Spectroscopy

Xiaohui Li, Xue Chen, Yao Zhang, Sibo Yang, Guodong Yao, Aichun Liu, and Xin Yu

CLEO: Applications and Technology 2020

Washington, DC United States
10–15 May 2020
ISBN: 978-1-943580-76-7

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Photonic Cancer and Tissue Diagnostics (AM4I)

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X. Li, X. Chen, Y. Zhang, S. Yang, G. Yao, A. Liu, and X. Yu, "Elemental Mapping of Paraffin-Embedded Ductal Carcinoma Using Laser-Induced Breakdown Spectroscopy," in Conference on Lasers and Electro-Optics, OSA Technical Digest (Optica Publishing Group, 2020), paper AM4I.2.

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Abstract

We present multi-elemental mapping of paraffine-embedded ductal carcinoma tissues using laser-induced breakdown spectroscopy (LIBS). Distributions of major elements (Ca, K, Mg, Na) were obtained. Automatic discrimination of malignant and non-malignant regions was achieved using cluster analysis.

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