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Conferences > CLEO_AT > 2013 > AF1L > AF1L.2

Label-Free Kinetic Screening Of Proteins And Virus Binding In A 51,200 Small-Molecule Library With A High-Throughput Ellipsometric Scanning Microscope

Galina Malovichko, James P. Landry, Andrew P. Proudian, and Xiangdong Zhu

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Abstract

Using a label-free high-throughput optical scanning microscope we detected endpoints and binding kinetics of RNPC1a, Pyl(1&2) proteins and influenza virus A/PR/8/34 with a library of 51,200 small-molecule compounds from the NCI Developmental Therapeutics Program.

© 2013 Optical Society of America

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