Label-Free Quantitative Polymerase Chain Reaction in an Optical Fibre Microcavity

Xuegang Li; Xuegang Li; Linh V. Nguyen; Kelly Hill; Kelly Hill; Heike Ebendorff-Heidepriem; Heike Ebendorff-Heidepriem; Erik P. Schartner; Erik P. Schartner; Yong Zhao; Xue Zhou; Yanan Zhang; Stephen C. Warren-Smith; Stephen C. Warren-Smith

doi:10.1364/CLEOPR.2020.C11D_1

14th Pacific Rim Conference on Lasers and Electro-Optics (CLEO PR 2020)
OSA Technical Digest (Optica Publishing Group, 2020),
paper C11D_1
•https://doi.org/10.1364/CLEOPR.2020.C11D_1

Label-Free Quantitative Polymerase Chain Reaction in an Optical Fibre Microcavity

Xuegang Li, Linh V. Nguyen, Kelly Hill, Heike Ebendorff-Heidepriem, Erik P. Schartner, Yong Zhao, Xue Zhou, Yanan Zhang, and Stephen C. Warren-Smith

Conference on Lasers and Electro-Optics/Pacific Rim 2020

Sydney Australia
3–5 August 2020
ISBN: 978-0-646-82504-5

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Emerging Technologies in Biophotonics (C11D)

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X. Li, L. V. Nguyen, K. Hill, H. Ebendorff-Heidepriem, E. P. Schartner, Y. Zhao, X. Zhou, Y. Zhang, and S. C. Warren-Smith, "Label-Free Quantitative Polymerase Chain Reaction in an Optical Fibre Microcavity," in 14th Pacific Rim Conference on Lasers and Electro-Optics (CLEO PR 2020), OSA Technical Digest (Optica Publishing Group, 2020), paper C11D_1.

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Abstract

We demonstrate quantitative polymerase chain reaction (qPCR) using an all-fibre all-optical device. Through direct optical measurement of the sample refractive index, we show the potential of the system to operate as a label-free qPCR system.

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