Using two-photon microscopy, we quantify changes in blood flow after photothrombotic occlusion of individual blood vessels in rat neocortex, and find that flow reverses direction at the first branch that lies downstream from localized clots.

© 2004 Optical Society of America

PDF Article
More Like This
Two-photon fluorescence microscopy of collateral blood flow following photothrombotic stroke in rat neocortex

Chris B. Schaffer, Ford F. Ebner, Nozomi Nishimura, Beth Friedman, Philbert S. Tsai, Lee F. Schroeder, Patrick D. Lyden, and David Kleinfeld
ThPP2 Frontiers in Optics (FiO) 2003

Two-Photon Imaging of Cortical Microvascular Blood Flow in Response to Single Vessel Occlusion

N. Nishimura, C. B. Schaffer, B. Friedman, P. S. Tsai, P. D. Lyden, and D. Kleinfeld
JMB2 Frontiers in Optics (FiO) 2005

Femtosecond Laser Ablation to Induce Occlusions in Single, Targeted Venules in Rat Brain

John Nguyen, Nozomi Nishimura, Costantino Iadecola, and Chris B. Schaffer
BMC6 Biomedical Optics (BIOMED) 2010


You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
Login to access Optica Member Subscription