Shimmering Holograms and the Measure of Life in Optical Coherence Imaging of Tumor Spheroids

P. Yu; D. D. Nolte; J. J. Turek; M. R. Melloch

Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science Conference
Technical Digest (Optica Publishing Group, 2003),
paper CMBB6

Shimmering Holograms and the Measure of Life in Optical Coherence Imaging of Tumor Spheroids

P. Yu, D. D. Nolte, J. J. Turek, and M. R. Melloch

Conference on Lasers and Electro-Optics 2003

Baltimore, Maryland United States
1–6 June 2003
ISBN: 1-55752-733-4

From the session
OCT II: Innovative Approaches to Imaging (CMBB)

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P. Yu, D. D. Nolte, J. J. Turek, and M. R. Melloch, "Shimmering Holograms and the Measure of Life in Optical Coherence Imaging of Tumor Spheroids," in Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science Conference, Technical Digest (Optica Publishing Group, 2003), paper CMBB6.

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Abstract

We acquired video-movies of shimmering holograms inside tumor spheroids using optical coherence imaging. The shimmering is attributed to organelle motility inside living cells, and ceases when metabolic or cross-linking poisons are delivered to the specimens.

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