Rapid imaging of deep-tissue motion with parallelized diffuse correlation spectroscopy

Shiqi Xu; Xi Yang; Pavan Chanda Konda; Roarke Horstmeyer

doi:10.1364/BRAIN.2021.BTh1B.3

Biophotonics Congress 2021
OSA Technical Digest (Optica Publishing Group, 2021),
paper BTh1B.3
•https://doi.org/10.1364/BRAIN.2021.BTh1B.3

Rapid imaging of deep-tissue motion with parallelized diffuse correlation spectroscopy

Shiqi Xu, Xi Yang, Pavan Chanda Konda, and Roarke Horstmeyer

Optics and the Brain 2021

Washington, DC United States
12–16 April 2021
ISBN: 978-1-943580-85-9

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Diffuse Optics: Methods (BTh1B)

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S. Xu, X. Yang, P. C. Konda, and R. Horstmeyer, "Rapid imaging of deep-tissue motion with parallelized diffuse correlation spectroscopy," in Biophotonics Congress 2021, C. Boudoux, K. Maitland, C. Hendon, M. Wojtkowski, K. Quinn, M. Schanne-Klein, N. Durr, D. Elson, F. Cichos, L. Oddershede, V. Emiliani, O. Maragò, S. Nic Chormaic, N. Pégard, S. Gibbs, S. Vinogradov, M. Niedre, K. Samkoe, A. Devor, D. Peterka, P. Blinder, and E. Buckley, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper BTh1B.3.

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Abstract

We present a highly parallelized approach to diffuse correlation spectroscopy (DCS) using a 32 × 32 single-photon avalanche diode (SPAD) array, which allows imaging dynamic scattering events buried deep within tissue phantom at a 2.5Hz frame rate without requiring any scanning or instrument movement.

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