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Conferences > BOSD > 1998 > BMB > BMB1
  • Biomedical Optical Spectroscopy and Diagnostics / Therapeutic Laser Applications
  • OSA Trends in Optics and Photonics (Optica Publishing Group, 1998),
  • paper BMB1
  • •https://doi.org/10.1364/BOSD.1998.BMB1

Detecting Optical Heterogeneities in Turbid Media Using Contrast Agents: Fluorescence vs Absorption

X. D. Li, B. Chance, and A. G. Yodh

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Abstract

The use of exogenous fluorophores has been explored as a means to enhance the sensitivity and specificity for the detection of heterogeneities in thick turbid media [1,2]. This approach relies on the fact that the fluorophore will preferentially accumulate in tumors, and that the fluorophore lifetime may vary with environmental factors such as tissue oxygenation, pH and glucose level.

© 1998 Optical Society of America

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